![Etil 1-(4-metoksifenil)-6-({4-nitrofenil)-7-oxo-4,5,6,7-tetrahydro{ {9}}H-pyrazolo[3,4-c]piridin-3-carboxylate](/uploads/202332977/ethyl-1-4-methoxyphenyl-6-4-nitrophenyl-724024843-677c-4cf7-9ad2-f3eed812fe7d.jpg?size=398x0)
![Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/uploads/202332977/ethyl-1-4-methoxyphenyl-6-4-nitrophenyl-724024843-677c-4cf7-9ad2-f3eed812fe7d.jpg)
Etil 1-(4-metoksifenil)-6-({4-nitrofenil)-7-oxo-4,5,6,7-tetrahydro{ {9}}H-pyrazolo[3,4-c]piridin-3-carboxylate
Pwen k ap fonn: 190-192 degre
Pwen bouyi: 658.7±55.0 degre (Prevwa)
dansite: 1.40
presyon vapè:0Pa a 25 degre
Tanperati depo: Sele nan sèk, Tanperati chanm
Solibilite: klowofòm (yon ti kras), acetat etil (yon ti kras)
pka:{{0}}.80±0.20(Prevwa)
Dekri teren
Ki sa ki apixaban entèmedyè CAS 536759-91-8?
Apixaban entèmedyè CAS 536759-91-8 se yon entèmedyè pharmaceutique ki fèt pou fabrike medikaman antikoagulan apixaban.
Ki jan yo fè sentèz?
Li pwodui pa yon pwosesis sentetik twa etap ki kòmanse ak 2,4,4-trimethylpentan-1-ol kòm materyèl prensipal la. Premyèman, li kondanse ak 3-kloro-2-methylpropene pou fòme yon aldeid, ki answit reyaji ak 1-cyano-3-(4-ethoxycarbonyl-piperazin{{ 11}}yl)-propan-2-ol pou fòme entèmedyè vle a.
Sèvi ak jaden medikal apixabanse to redwi risk konjesyon serebral ak anbolis sistemik nan adilt ki gen fibrilasyon atriyal ki pa valv, pou trete tronboz venn gwo twou san fon ak anbolis poumon, diminye risk pou renouvlab tronboz venn fon ak anbolis poumon, ak trete tronboz venn.
![ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/Content/uploads/2023786625/20230227151104ed7e408406f34a118a10cc08931bdc61.jpg?size=1772x0 "ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate")
![ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/Content/uploads/2023786625/20230227151034908e33e6afe74068be820ce0e3aa715e.jpg?size=1772x0 "ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate")
![ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/Content/uploads/2023786625/20230227151139bc789d0b1a974fb68378cff08cb768d4.jpg?size=1772x0 "ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate")
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